A mutation in the B chain coding region is associated with impaired proinsulin conversion in a family with hyperproinsulinemia.

Lignende værker

• Posttranslational cleavage of proinsulin is blocked by a point mutation in familial hyperproinsulinemia.
  af: Shibasaki, Y, et al.
  Udgivet: (1985)
• Familial hyperproinsulinemia. Two cohorts secreting indistinguishable type II intermediates of proinsulin conversion.
  af: Robbins, D C, et al.
  Udgivet: (1984)
• A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto).
  af: Yano, H, et al.
  Udgivet: (1992)
• Familial hyperproinsulinemia: partial characterization of circulating proinsulin-like material.
  af: Gabbay, K H, et al.
  Udgivet: (1979)
• Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II.
  af: Sizonenko, S V, et al.
  Udgivet: (1991)