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RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis
Axon degeneration is observed in neurodegenerative diseases and neuroinflammatory disorders, such as Alzheimer’s disease, Parkinson’s disease and multiple sclerosis. The molecular basis of this process remains largely unknown. Here, we show that mice deleted for the tumour suppressor LKB1 (also call...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Company of Biologists Limited
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046091/ https://ncbi.nlm.nih.gov/pubmed/21135058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.006833 |
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