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RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis

Axon degeneration is observed in neurodegenerative diseases and neuroinflammatory disorders, such as Alzheimer’s disease, Parkinson’s disease and multiple sclerosis. The molecular basis of this process remains largely unknown. Here, we show that mice deleted for the tumour suppressor LKB1 (also call...

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Bibliografiske detaljer
Main Authors: Sun, Gao, Reynolds, Richard, Leclerc, Isabelle, Rutter, Guy A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046091/
https://ncbi.nlm.nih.gov/pubmed/21135058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.006833
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