Geometry of the antitumor drug ditercalinium bisintercalated into d(CpGpCpG)2 by 1H NMR.

Rigid 7H-pyrido[4,3-c]carbazole dimers, such as Ditercalinium, are DNA bisintercalators that display high DNA affinity and strong antitumor properties. This activity appears crucially dependent on the geometry of their complexes with DNA. Therefore, structures of the complexes formed by the self-com...

Popoln opis

Bibliografske podrobnosti

izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Delbarre, A, Delepierre, M, Garbay, C, Igolen, J, Le Pecq, J B, Roques, B P
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1987
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2155
Oznake:	Označite Brez oznak, prvi označite!