Geometry of the antitumor drug ditercalinium bisintercalated into d(CpGpCpG)2 by 1H NMR.

Rigid 7H-pyrido[4,3-c]carbazole dimers, such as Ditercalinium, are DNA bisintercalators that display high DNA affinity and strong antitumor properties. This activity appears crucially dependent on the geometry of their complexes with DNA. Therefore, structures of the complexes formed by the self-com...

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Publikašuvnnas:	Proc Natl Acad Sci U S A
Váldodahkkit:	Delbarre, A, Delepierre, M, Garbay, C, Igolen, J, Le Pecq, J B, Roques, B P
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	National Academy of Sciences 1987
Fáttát:	Research Article
Liŋkkat:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2155
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