Kinetic Scaffolding Mediated by a Phospholipase C–β and G(q) Signaling Complex

Transmembrane signals initiated by a broad range of extracellular stimuli converge on nodes that regulate phospholipase C (PLC)–dependent inositol lipid hydrolysis for signal propagation. We describe how heterotrimeric guanine nucleotide–binding proteins (G proteins) activate PLC-βs and in turn are...

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Bibliografiske detaljer
Main Authors: Waldo, Gary L., Ricks, Tiffany K., Hicks, Stephanie N., Cheever, Matthew L., Kawano, Takeharu, Tsuboi, Kazuhito, Wang, Xiaoyue, Montell, Craig, Kozasa, Tohru, Sondek, John, Harden, T. Kendall
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046049/
https://ncbi.nlm.nih.gov/pubmed/20966218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1193438
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