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Kinetic Scaffolding Mediated by a Phospholipase C–β and G(q) Signaling Complex
Transmembrane signals initiated by a broad range of extracellular stimuli converge on nodes that regulate phospholipase C (PLC)–dependent inositol lipid hydrolysis for signal propagation. We describe how heterotrimeric guanine nucleotide–binding proteins (G proteins) activate PLC-βs and in turn are...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3046049/ https://ncbi.nlm.nih.gov/pubmed/20966218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1193438 |
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