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High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule.

Both interleukin 2 (IL-2) and epidermal growth factor (EGF) receptors exist in two forms that differ with respect to affinity for their ligand. Only the high-affinity receptors appear to be responsible for the proliferation signal delivered upon binding of the growth factor. Fibroblasts transfected...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bernard, O, Fazekas de St Groth, B, Ullrich, A, Green, W, Schlessinger, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104909/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2125
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