The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

BACKGROUND: Compromised epithelial barriers are found in dysplastic tissue of the gastrointestinal tract. Claudins are transmembrane proteins important for tight junctions. Claudins regulate the paracellular transport and are crucial for maintaining a functional epithelial barrier. Down-regulation o...

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Hlavní autoři: Bornholdt, Jette, Friis, Stine, Godiksen, Sine, Poulsen, Steen S, Santoni-Rugiu, Eric, Bisgaard, Hanne C, Lothe, Inger MB, Ikdahl, Tone, Tveit, Kjell M, Johnson, Egil, Kure, Elin H, Vogel, Lotte K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045986/
https://ncbi.nlm.nih.gov/pubmed/21310043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-65
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