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Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis

BACKGROUND: Clinical trials where cancer patients were treated with protease inhibitors have suggested that the serine protease, prostasin, may act as a tumour suppressor. Prostasin is proteolytically activated by the serine protease, matriptase, which has a very high oncogenic potential. Prostasin...

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Detalhes bibliográficos
Main Authors: Selzer-Plon, Joanna, Bornholdt, Jette, Friis, Stine, Bisgaard, Hanne C, Lothe, Inger MB, Tveit, Kjell M, Kure, Elin H, Vogel, Ulla, Vogel, Lotte K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717118/
https://ncbi.nlm.nih.gov/pubmed/19555470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-201
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