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The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
BACKGROUND: Compromised epithelial barriers are found in dysplastic tissue of the gastrointestinal tract. Claudins are transmembrane proteins important for tight junctions. Claudins regulate the paracellular transport and are crucial for maintaining a functional epithelial barrier. Down-regulation o...
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Main Authors: | , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
BioMed Central
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045986/ https://ncbi.nlm.nih.gov/pubmed/21310043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-65 |
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