Matrix Metalloproteinase 9 (MMP9) Expression in Preeclamptic Decidua and MMP9 Induction by Tumor Necrosis Factor Alpha and Interleukin 1 Beta in Human First Trimester Decidual Cells

Extravillous trophoblasts (EVTs) invade human decidua via sequential integrin-mediated binding and proteolysis of basement membrane proteins in the extracellular matrix (ECM). In preeclampsia, shallow EVT invasion impairs spiral artery and arteriole remodeling to reduce uteroplacental blood flow. Ex...

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Detalhes bibliográficos
Main Authors: Lockwood, Charles J., Oner, Ceyda, Uz, Yesim H., Kayisli, Umit A., Huang, S. Joseph, Buchwalder, Lynn F., Murk, William, Funai, Edmund F., Schatz, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045968/
https://ncbi.nlm.nih.gov/pubmed/18276934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.107.063743
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