Thrombin Regulates Soluble fms-Like Tyrosine Kinase-1 (sFlt-1) Expression in First Trimester Decidua : Implications for Preeclampsia

The primary placental defect in preeclampsia is shallow trophoblast invasion of the decidua leading to incomplete vascular transformation and inadequate uteroplacental perfusion. Soluble fms-like tyrosine kinase-1 (sFlt-1) seems to interfere with these events by inhibiting local angiogenesis and/or...

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Detalhes bibliográficos
Main Authors: Lockwood, Charles J., Toti, Paolo, Arcuri, Felice, Norwitz, Errol, Funai, Edmund F., Huang, Se-Te J., Buchwalder, Lynn F., Krikun, Graciela, Schatz, Frederick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829472/
https://ncbi.nlm.nih.gov/pubmed/17392178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060465
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