載入...
Site-specific labeling of T7 DNA polymerase with a conformationally sensitive fluorophore and its use in detecting single-nucleotide polymorphisms
Like most enzymes, DNA polymerases undergo a large conformational change on the binding of a correct nucleotide. To determine how the conformational change contributes to substrate specificity, we labeled the T7 DNA polymerase with a conformationally sensitive fluorophore at a position that provides...
Na minha lista:
| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045965/ https://ncbi.nlm.nih.gov/pubmed/18834851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.09.006 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|