Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire

BACKGROUND: Recent advances in massively parallel sequencing have increased the depth at which T cell receptor (TCR) repertoires can be probed by >3log10, allowing for saturation sequencing of immune repertoires. The resolution of this sequencing is dependent on its accuracy, and direct assessmen...

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Hlavní autoři: Nguyen, Phuong, Ma, Jing, Pei, Deqing, Obert, Caroline, Cheng, Cheng, Geiger, Terrence L
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045962/
https://ncbi.nlm.nih.gov/pubmed/21310087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-106
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