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Induction of NEIL1 and NEIL2 DNA glycosylases in aniline-induced splenic toxicity

The mechanisms by which aniline exposure elicits splenotoxic response, especially the tumorigenic response, are not well-understood. Earlier, we have shown that aniline-induced oxidative stress is associated with increased oxidative DNA damage in rat spleen. The base excision repair (BER) pathway is...

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Main Authors: Ma, Huaxian, Wang, Jianling, Abdel-Rahman, Sherif Z., Hazra, Tapas K., Boor, Paul J., Khan, M. Firoze
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045817/
https://ncbi.nlm.nih.gov/pubmed/21145906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2010.12.001
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