Deficient High-Affinity Binding of Pittsburgh Compound B in a Case of Alzheimer’s Disease

Radiolabeled Pittsburgh compound B (PIB) is a benzothiazole imaging agent that usually binds with high affinity, specificity, and stoichiometry to cerebral β-amyloid (Aβ) in patients with Alzheimer’s disease. Among a cohort of ten AD subjects examined postmortem, we describe a case of idiopathic, en...

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Bibliografiske detaljer
Main Authors: Rosen, Rebecca F., Ciliax, Brian J., Wingo, Thomas S., Gearing, Marla, Dooyema, Jeromy, Lah, James J., Ghiso, Jorge A., LeVine, Harry, Walker, Lary C.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045810/
https://ncbi.nlm.nih.gov/pubmed/19690877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-009-0583-3
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