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PIB binding in aged primate brain: Enrichment of high-affinity sites in humans with Alzheimer’s disease

Aged nonhuman primates accumulate large amounts of human-sequence amyloid β (Aβ) in the brain, yet they do not manifest the full phenotype of Alzheimer’s disease (AD). To assess the biophysical properties of Aβ that might govern its pathogenic potential in humans and nonhuman primates, we incubated...

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Detalhes bibliográficos
Main Authors: ROSEN, REBECCA F., WALKER, LARY C., LEVINE, HARRY
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891164/
https://ncbi.nlm.nih.gov/pubmed/19329226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.02.011
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