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Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells.

Endogenous oligonucleotides were found in trichloroacetic acid extracts of hamster lung fibroblasts and Tetrahymena cells. Peaks of radioactivity that eluted with retention times similar to oligonucleotide markers (5- to 50-mer) were found by HPLC in cells labeled briefly with 32Pi. Only minute amou...

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Detalhes bibliográficos
Main Authors: Plesner, P, Goodchild, J, Kalckar, H M, Zamecnik, P C
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC304556/
https://ncbi.nlm.nih.gov/pubmed/3470767
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