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Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells.

Endogenous oligonucleotides were found in trichloroacetic acid extracts of hamster lung fibroblasts and Tetrahymena cells. Peaks of radioactivity that eluted with retention times similar to oligonucleotide markers (5- to 50-mer) were found by HPLC in cells labeled briefly with 32Pi. Only minute amou...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Plesner, P, Goodchild, J, Kalckar, H M, Zamecnik, P C
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.1936
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