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Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells.

Endogenous oligonucleotides were found in trichloroacetic acid extracts of hamster lung fibroblasts and Tetrahymena cells. Peaks of radioactivity that eluted with retention times similar to oligonucleotide markers (5- to 50-mer) were found by HPLC in cells labeled briefly with 32Pi. Only minute amou...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Plesner, P, Goodchild, J, Kalckar, H M, Zamecnik, P C
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304556/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.7.1936
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