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Osteopontin reduced hypoxia-ischemia neonatal brain injury by suppression of apoptosis in a rat pup model

BACKGROUND AND PURPOSE: Osteopontin (OPN) is neuroprotective in ischemic brain injuries in adult experimental models, therefore, we hypothesized that OPN would provide neuroprotection and improve long term neurological function in the immature brain after hypoxic-ischemic (HI) injury. METHODS: HI wa...

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Detalhes bibliográficos
Main Authors: Chen, Wanqiu, Ma, Qingyi, Suzuki, Hidenori, Hartman, Richard, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045536/
https://ncbi.nlm.nih.gov/pubmed/21273567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.599118
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