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HIF-1α inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model

Hypoxia-inducible factor-1alpha (HIF-1α) has been considered as a regulator of both prosurvival and prodeath pathways in the nervous system. The present study was designed to elucidate the role of HIF-1α in neonatal hypoxic-ischemic (HI) brain injury. Rice-Vannucci model of neonatal hypoxic-ischemic...

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Autors principals: Chen, Wanqiu, Jadhav, Vikram, Tang, Jiping, Zhang, John H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638995/
https://ncbi.nlm.nih.gov/pubmed/18602008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.05.020
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