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Glibenclamide improves neurological function in neonatal hypoxia-ischemia in rats

Recent studies demonstrated that sulfonylurea receptor 1 (SUR 1) regulated nonselective cation channel, the NC(Ca-ATP) channel, is involved in brain injury in rodent models of stroke. Block of SUR 1 with sulfonylurea such as glibenclamide has been shown to be highly effective in reducing cerebral ed...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Zhou, Yilin, Fathali, Nancy, Lekic, Tim, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866656/
https://ncbi.nlm.nih.gov/pubmed/19306849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.03.010
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