Isoflurane post-treatment reduces neonatal hypoxic-ischemic brain injury in rats by S1P/PI3K/Akt pathway

BACKGROUND AND PURPOSE: Isoflurane, administered before or during cerebral ischemia, has been shown to exhibit neuroprotection in animal models of ischemic stroke. However, the underlying mechanism remains to be elucidated. In the present study we determined whether isoflurane post-treatment provide...

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Main Authors: Zhou, Yilin, Lekic, Tim, Fathali, Nancy, Ostrowski, Robert P., Martin, Robert D., Tang, Jiping, Zhang, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917259/
https://ncbi.nlm.nih.gov/pubmed/20508187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.583757
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