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Upstream open reading frames: Molecular switches in (patho)physiology
Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF-mediated translational control in the etiology of human diseases. A genetic mouse model...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
WILEY-VCH Verlag
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045505/ https://ncbi.nlm.nih.gov/pubmed/20726009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201000037 |
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