Upstream open reading frames: Molecular switches in (patho)physiology

Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF-mediated translational control in the etiology of human diseases. A genetic mouse model...

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Detalles Bibliográficos
Main Authors: Wethmar, Klaus, Smink, Jeske J, Leutz, Achim
Formato: Artigo
Idioma:Inglês
Publicado: WILEY-VCH Verlag 2010
Assuntos:
Prospects & Overviews
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045505/
https://ncbi.nlm.nih.gov/pubmed/20726009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201000037
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