Upstream open reading frames: Molecular switches in (patho)physiology

Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF-mediated translational control in the etiology of human diseases. A genetic mouse model...

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Bibliografiska uppgifter
Huvudupphovsmän: Wethmar, Klaus, Smink, Jeske J, Leutz, Achim
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY-VCH Verlag 2010
Ämnen:
Prospects & Overviews
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045505/
https://ncbi.nlm.nih.gov/pubmed/20726009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201000037
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