Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

BACKGROUND: The use of dried blood spots (DBS) samples in genomic workup has been limited by the relative low amounts of genomic DNA (gDNA) they contain. It remains to be proven that whole genome amplified DNA (wgaDNA) from stored DBS samples, constitutes a reliable alternative to gDNA. We wanted to...

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Библиографические подробности
Главные авторы: Winkel, Bo G, Hollegaard, Mads V, Olesen, Morten S, Svendsen, Jesper H, Haunsø, Stig, Hougaard, David M, Tfelt-Hansen, Jacob
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045282/
https://ncbi.nlm.nih.gov/pubmed/21306642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-22
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