Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

BACKGROUND: The use of dried blood spots (DBS) samples in genomic workup has been limited by the relative low amounts of genomic DNA (gDNA) they contain. It remains to be proven that whole genome amplified DNA (wgaDNA) from stored DBS samples, constitutes a reliable alternative to gDNA. We wanted to...

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Autores principales: Winkel, Bo G, Hollegaard, Mads V, Olesen, Morten S, Svendsen, Jesper H, Haunsø, Stig, Hougaard, David M, Tfelt-Hansen, Jacob
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Technical Advance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045282/
https://ncbi.nlm.nih.gov/pubmed/21306642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-22
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