Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells

AIMS/HYPOTHESIS: Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. We hypothesise that this unresponsiveness is due to a generalised immaturity of the metabolic pathways normally found in beta cells rather...

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Detaylı Bibliyografya
Asıl Yazarlar: Jermendy, A., Toschi, E., Aye, T., Koh, A., Aguayo-Mazzucato, C., Sharma, A., Weir, G. C., Sgroi, D., Bonner-Weir, S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045081/
https://ncbi.nlm.nih.gov/pubmed/21240476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-2036-x
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