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Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells
AIMS/HYPOTHESIS: Fetal and neonatal beta cells have poor glucose-induced insulin secretion and only gain robust glucose responsiveness several weeks after birth. We hypothesise that this unresponsiveness is due to a generalised immaturity of the metabolic pathways normally found in beta cells rather...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3045081/ https://ncbi.nlm.nih.gov/pubmed/21240476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-2036-x |
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