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β-cell dedifferentiation in diabetes is important, but what is it?

This commentary discusses the concept of β-cell dedifferentiation in diabetes, which is important but not well defined. A broad interpretation is that a state of differentiation has been lost, which means changes in gene expression as well as in structural and functional elements. Thus, a fully matu...

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書目詳細資料
Main Authors: Weir, Gordon C, Aguayo-Mazzucato, Cristina, Bonner-Weir, Susan
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010577/
https://ncbi.nlm.nih.gov/pubmed/24356710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/isl.27494
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