Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl.
Aldose reductase [aldehyde reductase 2; alditol:NAD(P)+ 1-oxidoreductase, EC 1.1.1.21] catalyzes conversion of glucose to sorbitol. Although its activity is implicated in the progression of ocular and neurological complications of diabetes, the normal function of the enzyme in most cells is unknown....
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1987
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304508/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3104902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.6.1718 |
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