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Structure-Function Analysis of VPS9-Ankyrin-repeat Protein (Varp) in the Trafficking of Tyrosinase-related Protein 1 in Melanocytes

Because Varp (VPS9-ankyrin-repeat protein)/Ankrd27 specifically binds two small GTPases, Rab32 and Rab38, which redundantly regulate the trafficking of melanogenic enzymes in mammalian epidermal melanocytes, it has recently been implicated in the regulation of trafficking of a melanogenic enzyme tyr...

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Bibliografske podrobnosti
Main Authors: Tamura, Kanako, Ohbayashi, Norihiko, Ishibashi, Koutaro, Fukuda, Mitsunori
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045006/
https://ncbi.nlm.nih.gov/pubmed/21187289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191205
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