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FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress

Transcriptional regulatory mechanisms of cardiac oxidative stress resistance are not well defined. FoxO transcription factors are critical mediators of oxidative stress resistance in multiple cell types, but cardioprotective functions have not been reported previously. FoxO function in oxidative str...

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Detalles Bibliográficos
Main Authors: Sengupta, Arunima, Molkentin, Jeffery D., Paik, Ji-Hye, DePinho, Ronald A., Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045002/
https://ncbi.nlm.nih.gov/pubmed/21159781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.179242
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