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FoxO and FoxM1 Transcription Factors Have Antagonistic Functions in Neonatal Cardiomyocyte Cell Cycle Withdrawal and IGF1 Gene Regulation

RATIONALE: In the mammalian heart, cardiomyocytes withdraw from the cell cycle and initiate hypertrophic growth soon after birth, but the transcriptional regulatory mechanisms that control these neonatal transitions are not well-defined. OBJECTIVE: Forkhead family transcription factors have been imp...

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Autori principali: Sengupta, Arunima, Kalinichenko, Vladimir V., Yutzey, Katherine E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548965/
https://ncbi.nlm.nih.gov/pubmed/23152492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.277442
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