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Adaptive seeds tame genomic sequence comparison

The main way of analyzing biological sequences is by comparing and aligning them to each other. It remains difficult, however, to compare modern multi-billionbase DNA data sets. The difficulty is caused by the nonuniform (oligo)nucleotide composition of these sequences, rather than their size per se...

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Autors principals: Kiełbasa, Szymon M., Wan, Raymond, Sato, Kengo, Horton, Paul, Frith, Martin C.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044862/
https://ncbi.nlm.nih.gov/pubmed/21209072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113985.110
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