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Parameters for accurate genome alignment

BACKGROUND: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which score parameters to use. Surprisingly, there has been no large-scale assessment of these choices using real genomic data. Mo...

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Autors principals: Frith, Martin C, Hamada, Michiaki, Horton, Paul
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829014/
https://ncbi.nlm.nih.gov/pubmed/20144198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-80
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