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Parameters for accurate genome alignment

BACKGROUND: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which score parameters to use. Surprisingly, there has been no large-scale assessment of these choices using real genomic data. Mo...

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Detalhes bibliográficos
Main Authors: Frith, Martin C, Hamada, Michiaki, Horton, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829014/
https://ncbi.nlm.nih.gov/pubmed/20144198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-80
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