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Split-alignment of genomes finds orthologies more accurately

We present a new pair-wise genome alignment method, based on a simple concept of finding an optimal set of local alignments. It gains accuracy by not masking repeats, and by using a statistical model to quantify the (un)ambiguity of each alignment part. Compared to previous animal genome alignments,...

詳細記述

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書誌詳細
出版年:Genome Biol
主要な著者: Frith, Martin C, Kawaguchi, Risa
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464727/
https://ncbi.nlm.nih.gov/pubmed/25994148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0670-9
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