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Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription

We have used a novel bubble-trapping procedure to construct nearly pure and comprehensive human origin libraries from early S- and log-phase HeLa cells, and from log-phase GM06990, a karyotypically normal lymphoblastoid cell line. When hybridized to ENCODE tiling arrays, these libraries illuminated...

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書誌詳細
主要な著者: Mesner, Larry D., Valsakumar, Veena, Karnani, Neerja, Dutta, Anindya, Hamlin, Joyce L., Bekiranov, Stefan
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044852/
https://ncbi.nlm.nih.gov/pubmed/21173031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.111328.110
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