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PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression

BACKGROUND: PINCH1, an adaptor protein containing five LIM domains, plays an important role in regulating the integrin-mediated cell adhesion, migration and epithelial-mesenchymal transition. PINCH1 is induced in the fibrotic kidney after injury, and it primarily localizes at the sites of focal adhe...

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Hlavní autoři: Wang, Dan, Li, Yingjian, Wu, Chuanyue, Liu, Youhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044754/
https://ncbi.nlm.nih.gov/pubmed/21390327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017048
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