A Population Genetic Approach to Mapping Neurological Disorder Genes Using Deep Resequencing

Deep resequencing of functional regions in human genomes is key to identifying potentially causal rare variants for complex disorders. Here, we present the results from a large-sample resequencing (n = 285 patients) study of candidate genes coupled with population genetics and statistical methods to...

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Autori principali: Myers, Rachel A., Casals, Ferran, Gauthier, Julie, Hamdan, Fadi F., Keebler, Jon, Boyko, Adam R., Bustamante, Carlos D., Piton, Amelie M., Spiegelman, Dan, Henrion, Edouard, Zilversmit, Martine, Hussin, Julie, Quinlan, Jacklyn, Yang, Yan, Lafrenière, Ronald G., Griffing, Alexander R., Stone, Eric A., Rouleau, Guy A., Awadalla, Philip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044677/
https://ncbi.nlm.nih.gov/pubmed/21383861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001318
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