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Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection

BACKGROUND: In principle, the elimination of malignancies by oncolytic virotherapy could proceed by different mechanisms - e.g. tumor cell specific oncolysis, destruction of the tumor vasculature or an anti-tumoral immunological response. In this study, we analyzed the contribution of these factors...

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Autori principali: Weibel, Stephanie, Raab, Viktoria, Yu, Yong A, Worschech, Andrea, Wang, Ena, Marincola, Francesco M, Szalay, Aladar A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044654/
https://ncbi.nlm.nih.gov/pubmed/21320309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-68
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