Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors

BACKGROUND: Oncolytic viruses, including vaccinia virus (VACV), are a promising alternative to classical mono-cancer treatment methods such as surgery, chemo- or radiotherapy. However, combined therapeutic modalities may be more effective than mono-therapies. In this study, we enhanced the effective...

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Detalhes bibliográficos
Main Authors: Schäfer, Simon, Weibel, Stephanie, Donat, Ulrike, Zhang, Qian, Aguilar, Richard J, Chen, Nanhai G, Szalay, Aladar A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495867/
https://ncbi.nlm.nih.gov/pubmed/22917220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-366
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