Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy

BACKGROUND: GLV-1h68 is an attenuated recombinant vaccinia virus (VACV) that selectively colonizes established human xenografts inducing their complete regression. RESULTS: Here, we explored xenograft/VACV/host interactions in vivo adopting organism-specific expression arrays and tumor cell/VACV in...

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Bibliographic Details
Main Authors: Worschech, Andrea, Chen, Nanhai, Yu, Yong A, Zhang, Qian, Pos, Zoltan, Weibel, Stephanie, Raab, Viktoria, Sabatino, Marianna, Monaco, Alessandro, Liu, Hui, Monsurró, Vladia, Buller, R Mark, Stroncek, David F, Wang, Ena, Szalay, Aladar A, Marincola, Francesco M
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713268/
https://ncbi.nlm.nih.gov/pubmed/19583830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-301
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