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Metabolic cross-talk allows labeling of O-linked β-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway

Hundreds of mammalian nuclear and cytoplasmic proteins are reversibly glycosylated by O-linked β-N-acetylglucosamine (O-GlcNAc) to regulate their function, localization, and stability. Despite its broad functional significance, the dynamic and posttranslational nature of O-GlcNAc signaling makes it...

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Detalhes bibliográficos
Main Authors: Boyce, Michael, Carrico, Isaac S., Ganguli, Anjali S., Yu, Seok-Ho, Hangauer, Matthew J., Hubbard, Sarah C., Kohler, Jennifer J., Bertozzi, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044403/
https://ncbi.nlm.nih.gov/pubmed/21300897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010045108
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