Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number

Antigen-driven expansion of specific CD4 T cells diminishes, on a per cell basis, as infused cell number increases. There is a linear relation between log precursor number and log factor of expansion (FE), with a slope of ∼−0.5 over a range from 3 to 30,000 precursors. Cell number dependence of FE i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Quiel, Juan, Caucheteux, Stephane, Laurence, Arian, Singh, Nevil J., Bocharov, Gennady, Ben-Sasson, Shlomo Z., Grossman, Zvi, Paul, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044359/
https://ncbi.nlm.nih.gov/pubmed/21292989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018525108
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky