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Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number
Antigen-driven expansion of specific CD4 T cells diminishes, on a per cell basis, as infused cell number increases. There is a linear relation between log precursor number and log factor of expansion (FE), with a slope of ∼−0.5 over a range from 3 to 30,000 precursors. Cell number dependence of FE i...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3044359/ https://ncbi.nlm.nih.gov/pubmed/21292989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018525108 |
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