Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes.

Antibodies binding to a large subset of T-cell differentiation antigens, including CD2, CD4, CD5, CD6, CD7, CD8, Tp44, and CDw18, cause an increase in the cytoplasmic calcium concentration [( Ca2+]i) after the antigens are crosslinked on the cell surface. Similar crosslinking-induced signals were se...

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Bibliographic Details
Main Authors: Ledbetter, J A, June, C H, Grosmaire, L S, Rabinovitch, P S
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304434/
https://ncbi.nlm.nih.gov/pubmed/3103134
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